{"id":104720,"date":"2025-01-09T11:59:01","date_gmt":"2025-01-09T17:59:01","guid":{"rendered":"https:\/\/engineering.wisc.edu\/?post_type=tribe_events&#038;p=104720"},"modified":"2025-01-09T11:59:03","modified_gmt":"2025-01-09T17:59:03","slug":"bme-seminar-series-jingwen-yan-phd","status":"publish","type":"tribe_events","link":"https:\/\/engineering.wisc.edu\/event\/bme-seminar-series-jingwen-yan-phd\/","title":{"rendered":"BME Seminar Series: Jingwen Yan, PhD"},"content":{"rendered":"<div  class=\"tribe-events-schedule tribe-clearfix\" >\n\t<h2 class=\"tribe-events-schedule__datetime\">\n\t\t<span class=\"tribe-events-schedule__date tribe-events-schedule__date--start\">\n\t\t\tJanuary 21\t\t<\/span>\n\n\t\t\t\t\t<span class=\"tribe-events-schedule__separator tribe-events-schedule__separator--date\">\n\t\t\t\t @ \t\t\t<\/span>\n\t\t\t<span class=\"tribe-events-schedule__time tribe-events-schedule__time--start\">\n\t\t\t\t12:00 PM\t\t\t<\/span>\n\t\t\n\t\t\t\t\t\t\t\t\t<span class=\"tribe-events-schedule__separator tribe-events-schedule__separator--time\">\n\t\t\t\t\t &#8211; \t\t\t\t<\/span>\n\t\t\t\n\t\t\t\t\t\t\t<span class=\"tribe-events-schedule__time tribe-events-schedule__time--end\">\n\t\t\t\t\t1:00 PM\t\t\t\t<\/span>\n\t\t\t\n\t\t\t\t\t\t<\/h2>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Integrative -omics for improved understanding and detection of Alzheimer\u2019s disease<\/h2>\n\n\n\n<figure class=\"wp-block-image alignright size-full\"><img data-dominant-color=\"918179\" data-has-transparency=\"false\" style=\"--dominant-color: #918179;\" loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/01\/Jingwen-Yan_headshot_seminar.avif\" alt=\"Jingwen Yan\" class=\"wp-image-104715 not-transparent\" srcset=\"https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/01\/Jingwen-Yan_headshot_seminar.avif 300w, https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/01\/Jingwen-Yan_headshot_seminar-256x256.avif 256w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n\n\n\n<p><strong>Jingwen Yan, PhD<br>Associate Professor and Director of Bioinformatics<br>Luddy School of Informatics, Computing and Engineering<br>Indiana University Indianapolis<\/strong><\/p>\n\n\n\n<p>Abstract:<br>Integrative -omics is an emerging research field that aims to extract the knowledge from the broad multi-omic data landscape. While multiple domains included, such as brain imaging, genetics, transcriptomics and proteomics, it offers great promise to illuminate the causal pathway from genotype to phenotype and to provide optimal molecular phenotypes for early therapeutic intervention. Building on the extensive mult-omics and brain imaging datasets, we focus on the development and application of AI models and bioinformatics approaches aimed at 1) exploring the functional mechanisms linked to Alzheimer risk variants (i.e., functional genomics) and 2) modeling disease progression to improve early detection and risk assessment. In this talk, I will introduce some of our recent work on exploration of AD molecular mechanisms and early detection with integrative -omics approaches.<\/p>\n\n\n\n<p><a href=\"https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/01\/Yan_BME-Seminar_Spring-2025.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Print PDF<\/a><\/p>\n\n\n<div  class=\"tribe-block tribe-block__organizer__details tribe-clearfix\" >\n\t<div class=\"tribe-block__organizer__title\">\n\t\t<h3><a href=\"https:\/\/engineering.wisc.edu\/organizer\/department-of-biomedical-engineering\/\" title=\"Department of Biomedical Engineering\" target=\"_self\" rel=\"\">Department of Biomedical Engineering<\/a><\/h3>\n\t<\/div>\n\t\t\t<p class=\"tribe-block__organizer__phone\">608-263-4660<\/p>\n\t\t\t\t<p class=\"tribe-block__organizer__website\"><a href=\"https:\/\/engineering.wisc.edu\/departments\/biomedical-engineering\/\" target=\"_self\" rel=\"external\">View Organizer Website<\/a><\/p>\n\t\t\t\t<p class=\"tribe-block__organizer__email\">bm&#101;hel&#112;&#064;&#098;m&#101;.&#119;is&#099;&#046;&#101;du<\/p>\n\t<\/div>\n\n\n<div  class=\"tribe-block tribe-block__venue tribe-clearfix tribe-block__venue--has-map\" >\n\t\n\t\n<div class=\"tribe-block__venue__meta\">\n\t<div class=\"tribe-block__venue__name\">\n\t\t<h3><a href=\"https:\/\/engineering.wisc.edu\/venue\/2180-mechanical-engineering\/\" title=\"2180 Mechanical Engineering\">2180 Mechanical Engineering<\/a><\/h3>\n\t<\/div>\n\n\t\n\t\t\t<address class=\"tribe-block__venue__address\">\n\t\t\t<span class=\"tribe-address\">\n\n<span class=\"tribe-street-address\">1513 University Ave<\/span>\n\t\n\t\t<br>\n\t\t<span class=\"tribe-locality\">Madison<\/span><span class=\"tribe-delimiter\">,<\/span>\n\n\t<abbr class=\"tribe-region tribe-events-abbr\" title=\"Wisconsin\">WI<\/abbr>\n\n\t<span class=\"tribe-postal-code\">53706<\/span>\n\n\t<span class=\"tribe-country-name\">United States<\/span>\n\n<\/span>\n\n\t\t\t\t\t\t\t<a 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class=\"tribe-events-c-subscribe-dropdown__list-item\">\n\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\t\t\thref=\"https:\/\/www.google.com\/calendar\/event?action=TEMPLATE&#038;dates=20250121T120000\/20250121T130000&#038;text=BME%20Seminar%20Series%3A%20Jingwen%20Yan%2C%20PhD&#038;details=%3Ch2+class%3D%22wp-block-heading%22%3EIntegrative+-omics+for+improved+understanding+and+detection+of+Alzheimer%E2%80%99s+disease%3C%2Fh2%3E%3Cfigure+class%3D%22wp-block-image+alignright+size-full%22%3E%3Cimg+src%3D%22https%3A%2F%2Fengineering.wisc.edu%2Fwp-content%2Fuploads%2F2025%2F01%2FJingwen-Yan_headshot_seminar.avif%22+alt%3D%22Jingwen+Yan%22+class%3D%22wp-image-104715%22%2F%3E%3C%2Ffigure%3E%3Cp%3E%3Cstrong%3EJingwen+Yan%2C+PhD%3Cbr+%2F%3EAssociate+Professor+and+Director+of+Bioinformatics%3Cbr+%2F%3ELuddy+School+of+Informatics%2C+Computing+and+Engineering%3Cbr+%2F%3EIndiana+University+Indianapolis%3C%2Fstrong%3E%3C%2Fp%3E+%3Cp%3EAbstract%3A%3Cbr+%2F%3EIntegrative+-omics+is+an+emerging+research+field+that+aims+to+extract+the+knowledge+from+the+broad+multi-omic+data+landscape.+While+multiple+domains+included%2C+such+as+brain+imaging%2C+genetics%2C+transcriptomics+and+proteomics%2C+it+offers+great+promise+to+illuminate+the+causal+pathway+from+genotype+to+phenotype+and+to+provide+optimal+molecular+phenotypes+for+early+therapeutic+intervention.+Building+on+the+extensive+mult-omics+and+brain+imaging+datasets%2C+w%3C%2Fp%3E+%28View+Full+event+Description+Here%3A+https%3A%2F%2Fengineering.wisc.edu%2Fevent%2Fbme-seminar-series-jingwen-yan-phd%2F%29&#038;location=2180%20Mechanical%20Engineering,%201513%20University%20Ave,%20Madison,%20WI,%2053706,%20United%20States&#038;trp=false&#038;ctz=America\/Chicago&#038;sprop=website:https:\/\/engineering.wisc.edu\"\n\t\t\t\t\t\t\t\t\t\tclass=\"tribe-events-c-subscribe-dropdown__list-item-link\"\n\t\t\t\t\t\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\t\t\t\trel=\"noopener 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365\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"tribe-events-c-subscribe-dropdown__list-item\">\n\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\t\t\thref=\"\"\n\t\t\t\t\t\t\t\t\t\tclass=\"tribe-events-c-subscribe-dropdown__list-item-link\"\n\t\t\t\t\t\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\t\t\t\trel=\"noopener noreferrer nofollow noindex\"\n\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\tOutlook Live\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\n\n<h2 class=\"tribe-block__related-events__title\">Related Events<\/h2>\n\n<ul  class=\"tribe-related-events tribe-clearfix\" >\n\t\t\t<li>\n\t\n<div class=\"tribe-related-events-thumbnail\">\n\t<a href=\"https:\/\/engineering.wisc.edu\/event\/isye-student-lunch\/\" class=\"url\" rel=\"bookmark\" tabindex=\"-1\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"768\" 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https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/02\/starlygraphic-512x288.avif 512w, https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/02\/starlygraphic-768x432.avif 768w, https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/02\/starlygraphic-1536x864.avif 1536w, https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2025\/02\/starlygraphic.avif 2000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" data-has-transparency=\"false\" data-dominant-color=\"a40c38\" style=\"--dominant-color: #a40c38;\" \/><\/a>\n<\/div>\n\t<div class=\"tribe-related-event-info\">\n\t<h3 class=\"tribe-related-events-title\">\n\t\t<a href=\"https:\/\/engineering.wisc.edu\/event\/isye-cyber-manufacturing-delivering-manufacturing-services-over-web-3-0\/\" class=\"tribe-event-url\" rel=\"bookmark\">\n\t\t\tISyE &#8211; Cyber-Manufacturing: Delivering Manufacturing Services Over Web 3.0\t\t<\/a>\n\t<\/h3>\n\t<span class=\"tribe-event-date-start\">March 14 @ 12:00 PM<\/span> &#8211; 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https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2024\/08\/Event-Graphics-for-Calendar-11-1536x864.avif 1536w, https:\/\/engineering.wisc.edu\/wp-content\/uploads\/2024\/08\/Event-Graphics-for-Calendar-11-jpg.avif 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" data-has-transparency=\"false\" data-dominant-color=\"900a09\" style=\"--dominant-color: #900a09;\" \/><\/a>\n<\/div>\n\t<div class=\"tribe-related-event-info\">\n\t<h3 class=\"tribe-related-events-title\">\n\t\t<a href=\"https:\/\/engineering.wisc.edu\/event\/mechanics-seminar-series-professor-franck-vernerey\/\" class=\"tribe-event-url\" rel=\"bookmark\">\n\t\t\tMechanics Seminar Series: Professor Franck Vernerey\t\t<\/a>\n\t<\/h3>\n\t<span class=\"tribe-event-date-start\">March 14 @ 12:05 PM<\/span> &#8211; <span class=\"tribe-event-time\">12:55 PM<\/span><\/div>\n<\/li>\n\t<\/ul>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Integrative -omics for improved understanding and detection of Alzheimer\u2019s disease Jingwen Yan, PhDAssociate Professor and Director of BioinformaticsLuddy School of Informatics, Computing and EngineeringIndiana University Indianapolis Abstract:Integrative -omics is an&#8230;<\/p>\n","protected":false},"author":92,"featured_media":102609,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_tec_requires_first_save":false,"_mbp_gutenberg_autopost":false,"_EventAllDay":false,"_EventTimezone":"America\/Chicago","_EventStartDate":"2025-01-21 12:00:00","_EventEndDate":"2025-01-21 13:00:00","_EventStartDateUTC":"2025-01-21 18:00:00","_EventEndDateUTC":"2025-01-21 19:00:00","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"$","_EventCurrencyCode":"USD","_EventCurrencyPosition":"prefix","_EventDateTimeSeparator":" @ ","_EventTimeRangeSeparator":" - 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